3 of the buddies have worthwhile bonuses and are best kept happy.
Little jacob: SPOILER: sells you guns cheaply at whatever location your at
Dwayne: SPOILER: sends 2 bullet catchers to help you on missions, handy to have around in the "you go 1st" sense, also if you kill him in the Holland play you ehh dont get the buddies
Roman: SPOILER: sends a cab to you for free, worth for the abuse the driver gives you about it being free
All of them need to kept happy to continue helped you out.
kdjac
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