While I agree with you on the art house movies being better part I have to say I thought TransAmerica was over-hyped, as was Motorcycle Diaries and Junebug. Haven't been to see Little Miss Sunshine yet, but the Squid and the Whale is top notch alright. Good indies I'd recommend this year are
Shooting Dogs (harsher tale of the Rwandan genocide than Hotel Rwanda)
Little Fish (good but not great movie, worth the watch just for Cate Blanchett)
Three Burials (great story)
Brick (again its worth a watch but don't believe the hype around it)
The Proposition (Ray Winstone always performs)
Bookmarks