A draw is a draw - you just get on with it in terms of who you're paired with.
City got the hardest draw in the northern UEFA Cup region in 2006 (IFK Gothenborg). The rest, as they say, is history. So it does happen - and to other clubs/leagues as well.
Re co-efficient ratings - the better you do, the easier the draw, so the better you'll do again. Not letting players go off on holiday during the weeks when you know yiou'll have Euro games would be a good starting point for IL teams if they want to stop getting such sh!tty draws....:o