Sure, why not.
In the US, if your driving is impaired because of antihistamines/ drowsy cough medicine etc and you are caught - you are subject to the very same DUI laws as alchohol.
As regards tiredness, let's say you are in an accident and there is evidence that the cause was fatigue - because you had just got off a trans atlantic overnight flight and then embarked on a long car journey ...... or you worked a 16 hour shift and then decided to drive half way across the country ...... you should be liable for that and whoever you've harmed should be able to sue the panse off you.
If you decide not to wear your prescriptive reading glasses and get in an accident because you are half blind, then they should throw your ass in jail.
Getting back to alchohol - my view is they should reduce the concentration to virtually zero. If you give people an inch, they'll take a mile (particularly in this country).
Now if you'll excuse me, I have a high horse I need to ride around the place ....