Surely LoI clubs want the grass trampled in front of them to progress in European Competition themselves. So the success of Anorthosis and BATE Borisov in their first leg match (so far/only) is a benefit to clubs who compete at the 1st qualifying stage (q1).
While both clubs can be considered underdogs, I think that UEFA are happy to promote the underdog in the CL. UEFA expand both competitions for the middle-ranked clubs aswell and if the middle clubs can be overtaken by experienced sides from below, so be it.